Flubromazepam is a long-acting benzodiazepine psychoactive substance that produces anxiolytic, soothing, relaxing muscles, inhibiting and forgetting effects.
The connection was originally made in 1960, but it was never on the market and received no additional attention or research until the end of 2012. It can be used for short-term treatment of anxiety, insomnia, acute seizures and sedation in hospitalized patients.
However, at present it is sold only by online research chemical suppliers for recreational psychoactive substances and is not officially studied. This means that any comments on its pharmacology are based solely on its subjective effects of induction and its structural similarity to triazolam, pyrazolam and other benzodiazepines.
It is worth noting that for people who are often used for long periods of time, sudden discontinuation of benzodiazepines may be potentially dangerous or life threatening, which sometimes leads to seizures or death. It is strongly recommended to gradually reduce the daily dose, rather than stop suddenly and gradually reduce the dose.
Chemistry of Flupromazepam
Flupromazepam or 7-bromo-5- (2-fluorophenyl) -1,3-dihydro-1,4-benzodiazepin-2-one is a benzodiazepine compound. Flubromazepam is named after the replacement of fluorine and bromine by its main benzodiazepine skeleton (FLUorine-BROMine-azepam). Flubromazepam is a member of benzodiazepines, since it contains a heterocycle of 1,4-diaza fused to a substituted benzene ring. Bromine binds to a bicyclic structure at R7. In addition, the fluorine-substituted benzene ring is attached to the structure at R5. Flubromazepam also contains an oxygen group attached to the double bond of R2 of its diazo heterocycle to form a ketone. The replacement of oxygen in R2 is shared with other benzodiazepines using the azepam suffix.
Benzodiazepines produce various effects by binding to the site of the benzodiazepine receptor and enhance the efficacy and action of the neurotransmitter gamma-aminobutyric acid (GABA) by acting on its receptor. Since this site is the most potent inhibitory receptor in the brain, its regulation leads to sedation (or sedation) of the nervous system by flurazepam.
The anticonvulsant properties of benzodiazepines can be partially or fully explained by binding to sodium channels that depend on stress, rather than benzodiazepine receptors.
The effects listed below are based on the subjective efficiency score and the personal experience of the authors of PsychonautWiki. This effect should be a grain of salt, and very little (if any) occurs simultaneously, but heavier doses increase the chances and most likely cause a full range of effects. Similarly, higher doses of adverse reactions are more likely and may involve severe trauma or death.
Tolerance and dependence
The body and mind of Flubromazepam are very addictive.
Within a few days of continuous use, tolerance will turn into a sedative-hypnotic effect. After stopping, tolerance returned to baseline after 7-14 days. However, in some cases this may take longer, which is proportional to the duration and intensity of long-term human use.
Symptoms of withdrawal or signs of rebound may occur after a sudden discontinuation of use after several weeks or more of a stable administration, and a gradual dose reduction may be required. For more information about the gradual reduction of benzodiazepines in a controlled manner, please refer to this manual.
It is very difficult to stop using benzodiazepines, which can endanger life for people who often use stopping without lowering the dose for several weeks. There is a risk of high blood pressure, seizures and death. Drugs that reduce the threshold of capture, such as tramadol, should be avoided during cancellation.
Flubromazepam is cross-tolerant to all benzodiazepines, which means that all benzodiazepines are less effective after consumption.